Calais and Mitchell each scored in the fourth quarter to help the Ragin' Cajuns (5-2, 2-1 Sun Belt Conference) pull away. Mitchell scored from 1 yard for a 30-20 lead with 6:19 left and Calais added a 38-yard TD run with 3:18 left.
Calais ran eight times for 144 yards and Mitchell ran 23 times for 109 yards.
The Red Wolves (3-4, 1-2) trailed 24-10 at halftime. Blake Grupe kicked a 46-yard field goal in the third quarter and Layne Hatcher threw a 25-yard TD pass to Kirk Merritt to cut the deficit to 24-20 early in the fourth.
Record-breaking Martin leads NC A&T past Bethune-Cookman
Jah-Maine Martin scored three touchdowns and had 120 yards rushing on 19 carries and North Carolina A&T beat Bethune-Cookman 47-17 on Saturday.
Rice gets first win, beats Middle Tennessee 31-28
Tom Stewart threw three touchdown passes, Aston Walter ran for 106 yards and Rice beat Middle Tennessee 31-28 on Saturday for its first win of the season.
UL-Lafayette beats South Alabama, stays atop Sun Belt West
Elijah Mitchell rushed 17 times for 117 yards and a touchdown and caught two passes for 20 yards to help Louisiana-Lafayette beat South Alabama 37-27 on Saturday night.
New Mexico State gets first win, 41-28 over Incarnate Word
Josh Adkins threw two touchdown passes, Jason Huntley ran for 174 yards and New Mexico State beat Incarnate Word 41-28 on Saturday for its first win of the season.
San Diego continues PFL dominance with 52-20 win
Reid Sinnett threw four touchdown passes and San Diego beat Morehead State 52-20 to clinch the Pioneer Football League championship on Saturday.
Gordon leads Washington State over Stanford 49-22
Anthony Gordon threw for 520 yards and five touchdowns as Washington State beat Stanford 49-22 on Saturday, to move within one win of becoming bowl eligible.