Giant Killers: These high seeds are in danger

Bagley gears up for season finale against UNC (0:49)

Marvin Bagley III leads Duke into one final regular-season showdown with North Carolina. Tune in on Saturday at 8:15 p.m. ET on ESPN for the rivalry. (0:49)

It has been a rocky year for the blue bloods. And it could get worse in March.

There's still some basketball to be played, and the difficulty of each team's path will crystallize on Selection Sunday, but right now, according to our Giant Killers model, the No. 1 and No. 2 seeds most vulnerable in the second round are Kansas and North Carolina. That's based on Kansas' (No. 1 seed) chance to defeat each of the No. 8 or No. 9 seeds in the latest Bracketology and UNC's (No. 2 seed) chance against the No. 7 or No. 10 seeds.