Jo Inge Berget scored twice as New York City FC began the era of coach Domenec Torrent with a 2-1 victory against Toronto FC on Sunday.
Real Salt Lake's Damir Kreilach and San Jose's Danny Hoesen scored second-half goals as the Earthquakes and RSL battled to a 1-1 draw on Saturday.
Clint Dempsey tied a franchise record while scoring his first goal of the season as the Seattle Sounders rallied to draw 1-1 with the Chicago Fire.
Laurent Ciman and Adama Diomande scored in the opening eight minutes and Los Angeles FC cruised to 2-0 victory over the Columbus Crew.
Forward Khiry Shelton scored in the 88th minute to cap a frantic comeback as Sporting Kansas City recorded a 3-2 victory over the Houston Dynamo.
Defender Tommy Smith headed in a corner kick on the final play of the game as the Colorado Rapids rallied for a 3-2 victory over Minnesota United.
Ignacio Piatti delivered a late clincher, and the Montreal Impact capitalized on an own goal to hand Orlando City its seventh straight loss.
The New York Red Bulls scored two goals while down a man to defeat FC Dallas 3-0 at Red Bull Arena on Saturday in Harrison, N.J.
Borek Dockal scored two goals, Ilsinho and Fafa Picault each added a goal on a penalty kick and the Philadelphia Union defeated the visiting Vancouv
O'Neill joins from Dutch side Excelsior and will count as a homegrown player eligible for selection after the secondary transfer window opens.
LAFC needed a late Latif Blessing goal to escape a scare from USL side Sacramento Republic and advance to the U.S. Open Cup quarterfinals.
Orlando City CEO Alex Leitao says he'd like to have a new coach hired in the next week, but iconic Brazilian midfielder Kaka isn't a candidate.
Landon Donovan and Leon are parting ways before the end of his contract, the club announced in a statement on Sunday.
The Philadelphia Union beat the New York Red Bulls 2-1 on Saturday to advance to the U.S. Open Cup quarterfinals.
Jason Kreis is out as Orlando City manager, with the Lions announcing his departure in the midst of the club's six-game MLS losing streak.
The San Jose Earthquakes announced the acquisition of defender Guram Kashia on Thursday.